NEEM is one of the most powerful blood-purifiers and detoxifiers in Ayurvedic usage. It cools the fever and clears the toxins involved in most inflammatory skin diseases or those found in ulcerated mucous membranes. It is a powerful febrifuge, effective in malaria and other intermittent and periodic fevers (in which case it is usually used with black pepper and gentian). Neem can be taken whenever a purification or reduction program is indicated. It clears away all foreign and excess tissue, and possesses a supplementary astringent action that promotes healing. Yet it should be used with discretion where there is severe fatigue or emaciation. In a medicated oil, it is one of the best healing and disinfectant agents for skin diseases, and anti-inflammatory agent for joint and muscle pain.